A case of ulcerative colitis complicated by oesophageal ulcers is reported.
A woman was admitted to our hospital because of exacerbations of ulcerativ
e colitis both in 1992 (aged 15 years) and 1995 (aged 18 years). When she w
as admitted in 1995 she complained of bloody diarrhoea, sore throat and pai
n on swallowing. Oesophagogastroduodenoscopy revealed oesophageal ulcers. O
esophageal pH monitoring (24-h) showed no evidence of gastrooesophageal ref
lux disease. After the patient was treated with Oral prednisolone she showe
d considerable improvement clinically and endoscopically. Initial dosage wa
s 60 mg/day, and 1 week later, the dosage was gradually dropped since the p
atient responded favourably. The improvement of the oesophageal lesions coi
ncided with the remission of ulcerative colitis. The oesophageal ulcers are
, therefore, thought to be an extracolonic manifestation of ulcerative coli
tis.