G. Alonso et al., Growth in four patients on combined treatment with LHRH analogue and growth hormone after renal transplantation, J PED END M, 13(7), 2000, pp. 941-943
Four short pubertal boys were treated with LHRHa (leuprolide) and GH after
renal transplantation, and followed until adult height. This combined thera
py was not successful in increasing growth. Although this study must be con
sidered preliminary because of the small number of patients and the lack of
a matched control group, it shows for the first time that this combined th
erapy (GH + LHRHa) administered to short, pubertal boys after renal transpl
antation was not successful in increasing growth. Further studies are requi
red to reach definitive conclusions.