Mw. Deboisblanc et al., Weaning injured patients with prolonged pulmonary failure from mechanical ventilation in a non-intensive care unit setting, J TRAUMA, 49(2), 2000, pp. 224-230
Background: Injured patients with pulmonary failure often require prolonged
length of stay in an intensive care unit (ICU), which includes weaning fro
m ventilatory support. In the last decade, noninvasive ventilation modes ha
ve been established as safe and effective. One method for accomplishing thi
s mode of ventilation uses a simple bilevel ventilator, Because this ventil
ator has been successfully used in hospital wards, we postulated that bilev
el ventilators could provide sufficient support during weaning from mechani
cal ventilation of injured patients in a non-ICU setting.
Methods: A retrospective review of trauma patients (August 1996-January 199
9) undergoing bilevel positive pressure ventilation as the final phase of w
eaning was conducted, Before ward transfer with bilevel ventilation, conven
tionally ventilated ICU patients were changed to bilevel ventilation and we
re required to tolerate this mode for at least 24 hours. Al patients had a
tracheostomy as a secure airway. Outcomes analyzed included ICU length of s
tay, hospital length of stay, duration of mechanical ventilation, weaning s
uccess, complications, and survival.
Results: Fifty-one patients (39 men, 12 women) with a mean age of 53 receiv
ed more than 24 hours of bilevel positive pressure ventilation. Mean Injury
Severity Score was 29, with blunt mechanisms of injury occurring in 90%, C
hest or spinal cord injuries that affected pulmonary mechanics were present
in 75% of patients. Ventilator-associated pneumonia was treated in 43% of
patients. Mean ICU length of stay and hospital length of stay were 21 and 3
4 days, respectively. Weaning was successful in 89% of patients, whereas 11
% were discharged to skilled nursing facilities still receiving bilevel pos
itive pressure ventilation. Two patients died, neither from a pulmonary nor
airway complication. Of the remaining 49 patients, 12 were weaned in the I
CU and 37 were transferred to the ward with bilevel ventilatory support. Th
e average length of ward ventilation was 6.5 +/- 5.4 days (n = 37),
Conclusions: Implementation of a program using bilevel ventilation to suppo
rt the terminal phase of weaning seriously injured patients from mechanical
ventilation was successful. After initiating this mode in the ICU, it was
satisfactorily continued in standard surgical wards. Because this method en
abled the withdrawal of ventilatory support in a non-ICU setting, its major
advantage was reducing ICU length of stay.