To characterize the circumstances surrounding initiation of injecting drug
use, data were collected from 229 young, recently initiated injection drug
users enrolled through community-based recruitment in Baltimore, Maryland.
Gender differences in the pattern of initiation, the number of persons pres
ent at initiation, risky injection, and sexual behaviors at initiation, as
well as behaviors after initiation, were examined. Overall, men and women w
ere similar statistically with respect to age at initiation (19.5 years) an
d risk behaviors at initiation. While men were initiated by men (77%), wome
n were more often. initiated by women (65%), most of whom were friends (75%
) or relatives (23%) The percentage of women infected with human immunodefi
ciency virus (HIV) was slightly greater than that of men, 17% versus 11% (P
< .2), whether initiated by a man or a woman. Persons who self-initiated h
ad a lower HIV prevalence and fewer HN-related risk behaviors. Analysis of
variance assessed differences in the HN risk profiles of female and male ID
Us who were initiated by someone of the same sex, of the opposite sex, or w
ho self-initiated. These results indicated that (1) young women and men had
similar patterns of injection initiation; (2) most women were initiated by
female friends, running counter to earlier literature claims that women we
re initiated to injection drug use by male sex partners; and (3) women init
iated by men had a marginally greater mean score on the HIV risk profile.