Adult T-cell leukemia/lymphoma (ATL) is a neoplastic disorder of T lymphocy
tes associated with human T lymphotropic virus type I (HTLV-I). The prognos
is of ATL is generally poor. We present here a 79-year-old woman with spont
aneous remission of acute type ATL. Spontaneous remission was preceded by s
urgical biopsy and pneumonia and lasted for two years until she died with p
ancreas cancer. Monoclonal integration of HTLV-I provirus DNA became undete
ctable after remission.