Molecular mechanisms of invasion by cancer cells, leukocytes and microorganisms

Authors
Lauwaet, T Oliveira, MJ Mareel, M Leroy, A
Citation
T. Lauwaet et al., Molecular mechanisms of invasion by cancer cells, leukocytes and microorganisms, MICROBES IN, 2(8), 2000, pp. 923-931
Citations number
53
Categorie Soggetti
Immunology
Journal title
MICROBES AND INFECTION
ISSN journal
12864579 → ACNP
Volume
2
Issue
8
Year of publication
2000
Pages
923 - 931
Database
ISI
SICI code
1286-4579(200007)2:8<923:MMOIBC>2.0.ZU;2-L
Abstract
Invasion is a phenotype common to cancer cells, leukocytes, parasites, bact eria and viruses, involving cell-cell adhesion, cell-matrix adhesion, prote olysis and motility. These activities are regulated by the cross talk betwe en invaders and host. We discuss the invasion-related molecular interaction s of E-cadherin, integrins, matrix metalloproteinases and the chemokine rec eptor RANTES. (C) 2000 Editions scientifiques et medicales Elsevier SAS.