Why do we lack an effective vaccine against herpes simplex virus infections?

Authors
Deshpande, SP Kumaraguru, U Rouse, BT
Citation
Sp. Deshpande et al., Why do we lack an effective vaccine against herpes simplex virus infections?, MICROBES IN, 2(8), 2000, pp. 973-978
Citations number
54
Categorie Soggetti
Immunology
Journal title
MICROBES AND INFECTION
ISSN journal
12864579 → ACNP
Volume
2
Issue
8
Year of publication
2000
Pages
973 - 978
Database
ISI
SICI code
1286-4579(200007)2:8<973:WDWLAE>2.0.ZU;2-1
Abstract
This review discusses the possible causes for the lack of an effective anti herpes vaccine. Future prospects of vaccines based on the current knowledge of immune responses to herpes viruses are discussed. It is argued that vac cines capable of expanding CD8 T-cell memory responses should be the focus of future anti-herpes simplex virus research. (C) 2000 Editions scientifiqu es et medicales Elsevier SAS.