Palladium-catalyzed synthesis of aqueous, fluorous, and supercritical CO2-soluble phosphines

Authors
Chen, WP Xu, LJ Xiao, JL
Citation
Wp. Chen et al., Palladium-catalyzed synthesis of aqueous, fluorous, and supercritical CO2-soluble phosphines, ORG LETT, 2(17), 2000, pp. 2675-2677
Citations number
46
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
17
Year of publication
2000
Pages
2675 - 2677
Database
ISI
SICI code
1523-7060(20000824)2:17<2675:PSOAFA>2.0.ZU;2-0
Abstract
[GRAPHICS] A generic, simple, and economical route has been developed for the synthesi s of phosphines soluble in aqueous, fluorous, and supercritical CO2 phases. The methodology is based on the palladium-catalyzed Heck olefination of ha loary/phosphine oxides followed by reduction, affording various arylphosphi nes in high yields.