Objective: To determine the incidence of appendiceal perforation (AP) among
children with acute appendicitis (AA) and determine factors associated wit
h AP.
Design: Retrospective chart review.
Setting: Emergency department (ED) of Primary Children's Medical Center (PC
MC).
Patients: 131 children less than 17 years of age with AA diagnosed in the P
CMC ED.
Results: The overall rate of AP was 47%. One hundred eleven (85%) children
with AA were correctly diagnosed on their first ED visit. Patients with AP
had a significantly (P < 0.05) lower median age (8.0 vs 11.0 gears), longer
duration of illness (3.0 vs 1.4 days), greater incidence of vomiting and f
ever by history (91% vs 69% and 83% vs 58%, respectively), higher median te
mperatures (39.0 degrees vs 38.3 degrees C), and higher proportions of leuk
ocyte (WBC) band forms (14% vs 5%). Patients with AP did not differ from th
ose without AP with respect to total WBC count, hour of arrival, or number
of ED visits.
Conclusions: The rate of AP among pediatric patients with AA is greater amo
ng younger children and is associated with vomiting, prolonged illness, and
higher body temperatures. Unexpectedly, patients with AP did not have high
er total WBC values, more frequent late night arrivals, a longer time inter
val prior to surgery, or more ED visits prior to diagnosis. These findings
suggest that efforts to decrease the rate of AP should be directed toward h
eightening awareness among primary care physicians regarding the high rate
of AP in children, with an emphasis on early ED and surgical referral.