Pelargoniins, new ellagitannins from Pelargonium reniforme

The range of natural ellagitannins is extended by identification of five ne w metabolites with C-1(4) glucose core, designated as pelargoniins A-D and isocorilagin, and the new phyllanthusiin E methyl ester. They are accompani ed in the aerial parts of Pelargonium reniforme by two known structurally r elated metabolites, corilagin and phyllanthusiin C, two phenolcarboxylic ac ids, brevifolincarboxylic acid and phyllanthusiin E, the gallotannin 1-O-ga lloyl-beta-D-glucopyranose, and the ellagitannins strictinin and isostricti nin having a C-4(1)-glucose core. The structures of these compounds were es tablished from spectroscopic studies. This is the first example of the co-o ccurrence of ellagitannins with C-4(1) and C-1(4) glucopyranose core demons trated for a member of the Geraniaceae. (C) 2000 Elsevier Science Ltd. All rights reserved.