This paper discusses the interaction between chitosan and the polyphenols s
eparated from spruce wood bark. The chitosan and the polyphenols formed a c
omplex and the release of the polyphenols occurred only in an alkaline medi
um (pH > 9) in a two-step process. Analysis of the release of the polypheno
ls showed that in the initial stage the diffusion occurs according to the F
ick's law, while in the last stage, the process develops according to a zer
o-order kinetics. (C) 2000 Elsevier Science B.V. All rights reserved.