Jp. Claverys et al., Is the Ami-AliA/B oligopeptide permease of Streptococcus pneumoniae involved in sensing environmental conditions?, RES MICROB, 151(6), 2000, pp. 457-463
Streptococcus pneumoniae is a fastidious obligate parasite requiring severa
l amino acids for growth. Oligopeptide uptake mediated by the Ami ABC perme
ase is therefore important for nutrition but this could not account for the
highly pleiotropic phenotype exhibited by Ami mutants. The hypothesis that
peptide transport plays a pivotal role in sensing environmental conditions
and indirectly modulates the expression of several genes is discussed. (C)
2000 Editions scientifiques et medicales Elsevier SAS.