Abnormal microcirculation and temperature in skin above tender points in patients with fibromyalgia

Objective. Skin temperature and skin blood flow were studied above differen t tender points in 20 patients with fibromyalgia (FM) and 20 healthy contro ls. Methods. Blood flow was measured by laser Doppler flowmetry and skin temper ature was measured with an infrared thermometer. Results. In the skin above the five tender points examined in each subject, we found an increased concentration of erythrocytes, decreased erythrocyte velocity and a consequent decrease in the flux of erythrocytes. A decrease in temperature was recorded above four of the five tender points. Conclusion. Vasoconstriction occurs in the skin above tender points in FM p atients, supporting the hypothesis that FM is related to local hypoxia in t he skin above tender points.