Jh. Patterson et Rp. Hamernik, BLAST OVERPRESSURE INDUCED STRUCTURAL AND FUNCTIONAL-CHANGES IN THE AUDITORY-SYSTEM, Toxicology, 121(1), 1997, pp. 29-40
Blast overpressure of sufficient intensity can produce injury to vario
us organ systems. Unprotected ears result in the auditory system being
the most susceptible. The injuries to the auditory system include: ru
pture of the tympanic membrane, dislocation or fracture of the ossicul
ar chain, and damage to the sensory structures on the basilar membrane
. All these injuries can be characterized as a form of mechanical dama
ge to the affected structure. Injury to the sensory structures on the
basilar membrane leads to temporary and permanent loss of hearing sens
itivity. The temporary component of the hearing loss shows a time cour
se after removal from the noise which frequently will include an initi
al increase in hearing loss followed by a recovery period during which
threshold may return to preexposure levels or stabilize at a higher l
evel which represents a permanent loss of hearing sensitivity. This ty
pe of recovery function suggests that there are damage processes which
continue after the traumatic event and that intervention might mitiga
te some of the damage and hearing loss. (C) 1997 Elsevier Science Irel
and Ltd.