Regio- and enantioselective siloxybutylation at the more hindered alpha-site of unsymmetrical ketone using chiral aluminum trisnaphthoxide

Authors
Saito, S Nakadai, M Yamamoto, H
Citation
S. Saito et al., Regio- and enantioselective siloxybutylation at the more hindered alpha-site of unsymmetrical ketone using chiral aluminum trisnaphthoxide, SYNLETT, (8), 2000, pp. 1107-1110
Citations number
21
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
8
Year of publication
2000
Pages
1107 - 1110
Database
ISI
SICI code
0936-5214(200008):8<1107:RAESAT>2.0.ZU;2-A
Abstract
A regio- and enantioselective siloxybutylation at the more hindered alpha-s ite of unsymmetrical dialkyl ketones was achieved to give a quarternary car bon center by the combined use of the chiral aluminum trisnaphthoxide (R)-A TBN and a base.