C. Pilger et al., A new stereoselective approach towards the galanthamine ring system via anintramolecular Heck reaction, SYNLETT, (8), 2000, pp. 1163-1165
We have developed a new synthetic access to the galanthamine ring structure
employing a stereoselective intramolecular Heck reaction as the key step.
Our route also allows for variation of the c- and d-ring sizes of galantham
ine which has not been reported so far.