Efficient synthesis of the C1-C8 fragment of reveromycins

Authors
Drouet, KE Tran, HV Theodorakis, EA
Citation
Ke. Drouet et al., Efficient synthesis of the C1-C8 fragment of reveromycins, SYN COMMUN, 30(19), 2000, pp. 3617-3628
Citations number
21
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
30
Issue
19
Year of publication
2000
Pages
3617 - 3628
Database
ISI
SICI code
0039-7911(2000)30:19<3617:ESOTCF>2.0.ZU;2-2
Abstract
A stereocontrolled synthesis of the Cl-C8 fragment of reveromycins is prese nted herein. Key to our strategy was the implementation of Evans' aldol rea ction that delivered the desired stereochemistry at the C4 and C5 stereocen ters.