Enantioselective addition of diethylzinc to aldehydes catalyzed by optically active 1,4-aminoalcohols

Authors
Hanyu, N Aoki, T Mino, T Sakamoto, M Fujita, T
Citation
N. Hanyu et al., Enantioselective addition of diethylzinc to aldehydes catalyzed by optically active 1,4-aminoalcohols, TETRAHEDR-A, 11(14), 2000, pp. 2971-2979
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
11
Issue
14
Year of publication
2000
Pages
2971 - 2979
Database
ISI
SICI code
0957-4166(20000728)11:14<2971:EAODTA>2.0.ZU;2-0
Abstract
Enantioselective addition reactions of diethylzinc to aldehydes were perfor med by catalytic reactions with chiral 1,4-aminoalcohols, Optically active 1,4-aminoalcohols were synthesized from (+)-camphor and (-)-fenchone throug h foul steps involving iodine-mediated lactonization of 3-hydroxy acids. (C ) 2000 Elsevier Science Ltd. All rights reserved.