S. Cristina et al., Lymphoepithelioma-like carcinoma of the breast. An unusual pattern of infiltrating lobular carcinoma, VIRCHOWS AR, 437(2), 2000, pp. 198-202
Citations number
34
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY
A case of breast carcinoma, showing both lymphoepithelioma-like and lobular
infiltrating carcinoma, is described, which must be distinguished from the
medullary carcinoma with which it shares some features, such as the strong
lymphocytic infiltration, but not sharp circumscription, syncytial growth
pattern, nuclear pleomorphism, and high mitotic rate. Unlike the lymphoepit
helial carcinoma of the nasopharynx and some lymphoepithelioma-like carcino
mas of the lung, stomach, salivary glands, and thymus, it does not seem to
be connected with Epstein-Barr virus (EBV) infection, as shown by negative
results of both in situ hybridization and polymerase chain reaction. This n
eoplasia may be defined as a peculiar form of lobular carcinoma, therefore,
more representative of an unusual microscopic pattern than a distinctive c
linicopathologic entity in itself.