Synthesis and properties of selected 4-substituted anhydro sugars

Authors
Abdel-Jalil, RJ Saeed, M Heeg, P Voelter, W
Citation
Rj. Abdel-jalil et al., Synthesis and properties of selected 4-substituted anhydro sugars, Z NATURFO B, 55(7), 2000, pp. 661-666
Citations number
17
Categorie Soggetti
Chemistry
Journal title
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
ISSN journal
09320776 → ACNP
Volume
55
Issue
7
Year of publication
2000
Pages
661 - 666
Database
ISI
SICI code
0932-0776(200007)55:7<661:SAPOS4>2.0.ZU;2-L
Abstract
A new class of 4-deoxy-4-([4-substituted-1-piperazinyl], [4-morpholinyl] an d [4-(perhydro-1,4-thiazin-4-yl)])-2,3-anhydrolyxopyranosides (3a-g and 6a- g) were synthesized from epoxy triflate moities 2 and 5 and 4-substituted p iperazines, morpholines and perhydro-1,4-thiazines, respectively, to test t heir antibacterial activity. The characterized series of new compounds was tested in vitro against E. coli ATCC11229, S. aureus ATCC6538 and C. albica ns SATCC10231.