Severe pancytopenia after leflunomide in rheumatoid arthritis

Authors
Auer, J Hinterreiter, M Allinger, S Kirchgatterer, A Knoflach, P
Citation
J. Auer et al., Severe pancytopenia after leflunomide in rheumatoid arthritis, ACT MED AUS, 27(4), 2000, pp. 131-132
Citations number
4
Categorie Soggetti
General & Internal Medicine
Journal title
ACTA MEDICA AUSTRIACA
ISSN journal
03038173 → ACNP
Volume
27
Issue
4
Year of publication
2000
Pages
131 - 132
Database
ISI
SICI code
0303-8173(2000)27:4<131:SPALIR>2.0.ZU;2-Q
Abstract
Leflunomide is a novel drug recently introduced for treatment of rheumatoid arthritis as a DMARD (disease-modifying antirheumatic drug). So far, leflu nomide has not been associated with severe bone marrow toxicity and pancyto penia. We report of a 62-year-old woman with a 14-year history of rheumatoi d arthritis with bone marrow toxicity and reversible pancytopenia developin g after treatment with leflunomide.