Zl. Chen et al., Estimation of formation constants of ternary Cu(II) complexes with mixed amino acid enantiomers based on ligand exchange by capillary electrophoresis, ANAL SCI, 16(8), 2000, pp. 837-841
Based on the principle of ligand exchange, a new method for estimating the
formation constants of ternary Cu(II) complexes with mixed amino acid enant
iomers has been proposed by capillary electrophoresis. As examples, the for
mation constants of four complexes, namely (L-OH-Pro)Cu(II)(D-Phe), (L-OH-P
ro)Cu(II)(L-Phe), (L-OH-Pro)Cu(II)(D-Trp) and (L-OH-Pro)Cu(II) (L-Trp), wer
e estimated by this method. The dependence of stability of complexes on the
stereo-selectivity and the possibility of predicting the enantiomer migrat
ion order from complex stability has been discussed.