Gadolinium-based contrast: An alternative contrast agent for endovascular interventions

The radiocontrast substance gadoterate meglumine (Gd-DOTA) is used in magne tic resonance imaging. Because of its low rate of adverse drug reactions, w e evaluated Gd-DOTA as an alternative contrast medium in diagnostic and the rapeutic procedures. Twenty-three consecutive procedures were performed usi ng undiluted contrast agent Gd-DOTA (376.9 mg/mL, Dotarem) in digital subtr action techniques. A dosage of 30-90 mt was used. Serum creatinine levels w ere registered before and at 24 and 48 hr after the procedure. Based on thi s limited experience, Gd-DOTA may be used as an alternative contrast agent in selected endovascular procedures, when iodine is contraindicated. DOI: 1 0.1007/s100169910085.