Natural product derived inhibitors of lipoprotein associated phospholipaseA(2), synthesis and activity of analogues of SB-253514

Authors
Pinto, IL Boyd, HF Hickey, DMB
Citation
Il. Pinto et al., Natural product derived inhibitors of lipoprotein associated phospholipaseA(2), synthesis and activity of analogues of SB-253514, BIOORG MED, 10(17), 2000, pp. 2015-2017
Citations number
10
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
17
Year of publication
2000
Pages
2015 - 2017
Database
ISI
SICI code
0960-894X(20000904)10:17<2015:NPDIOL>2.0.ZU;2-R
Abstract
The synthesis of analogues of SB-253514, a novel natural product derived in hibitor of lipoprotein associated phospholipase A(2) (Lp-PLA(2)), is descri bed together with their ability to inhibit Lp-PLA(2). (C) 2000 Elsevier Sci ence Ltd. All rights reserved.