Molecular topology: A useful tool for the search of new antibacterials

Authors
Alapont, CD Garcia-Domenech, R Galvez, J Ros, MJ Wolski, S Garcia, MD
Citation
Cd. Alapont et al., Molecular topology: A useful tool for the search of new antibacterials, BIOORG MED, 10(17), 2000, pp. 2033-2036
Citations number
16
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
17
Year of publication
2000
Pages
2033 - 2036
Database
ISI
SICI code
0960-894X(20000904)10:17<2033:MTAUTF>2.0.ZU;2-T
Abstract
Molecular topology has been applied to find new lead antibacterial compound s. Among the selected compounds, hesperidin, neohesperidin and Mordant Brow n 24 stand out, with minimum inhibitory concentrations 90, MIC90 < 0.3 mg/m L. (C) 2000 Elsevier Science Ltd. All rights reserved.