Growth regulation by insulin-like growth factor-I in fish

Authors
Moriyama, S Ayson, FG Kawauchi, H
Citation
S. Moriyama et al., Growth regulation by insulin-like growth factor-I in fish, BIOS BIOT B, 64(8), 2000, pp. 1553-1562
Citations number
93
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
64
Issue
8
Year of publication
2000
Pages
1553 - 1562
Database
ISI
SICI code
0916-8451(200008)64:8<1553:GRBIGF>2.0.ZU;2-8
Abstract
Insulin-like growth factor-I (IGF-I) is a mitogenic polypeptide that plays an essential role in the regulation of development and somatic growth of ve rtebrates, mainly by mediating growth hormone actions. It has clearly been established that the structure of IGF-I and its biological function has bee n highly conserved among vertebrates. In this paper, we review the recent d evelopments in the molecular, biochemical, and physiological properties of ICF-I in fish.