Scintigraphic evolution of a breast cancer with Tc-99m MIBI scintimammography

Early detection and prompt treatment of breast cancer are the main tools to decrease mortality rates, Several diagnostic techniques such as mammograph y, magnetic resonance imaging, and ultrasound are used, but none of these a re conclusive. The authors describe a 56-year-old woman who was suspected o f having breast cancer on mammography. Tc-99m MIBI scintimammography showed a small mass with elevated radiotracer uptake located near the pectoral mu scle of the patient's left breast. The possible tumor was confirmed with fi ne-needle aspiration biopsy, After the diagnosis was established, the patie nt did not allow any treatment. Eighteen months later, a second scintimammo graphy was performed, showing a large mammary tumor with a high radiotracer uptake, a new small lesion located in the left upper quadrant, and axillar y lymph node involvement. Chemotherapy treatment was instituted and after t reatment, Tc-99m MIBI scintimammography was normal. This case report provid es further evidence for Tc-99m MIBI scintimammography for the detection of breast cancer as well as to evaluate the response to chemotherapy.