Potassium channels: Watching a voltage-sensor tilt and twist

Authors
Sansom, MSP
Citation
Msp. Sansom, Potassium channels: Watching a voltage-sensor tilt and twist, CURR BIOL, 10(5), 2000, pp. R206-R209
Citations number
18
Categorie Soggetti
Experimental Biology
Journal title
CURRENT BIOLOGY
ISSN journal
09609822 → ACNP
Volume
10
Issue
5
Year of publication
2000
Pages
R206 - R209
Database
ISI
SICI code
0960-9822(20000309)10:5<R206:PCWAVT>2.0.ZU;2-1
Abstract
The fourth transmembrane helix (S4) is the primary voltage-sensor of voltag e-gated ion channels. Recent studies have used fluorescence resonance energ y transfer as a spectroscopic ruler to determine the nature and magnitude o f the voltage-induced movement of S4 that leads to channel opening.