Protein sorting: Recognizing mitochondrial presequences

Authors
Pfanner, N
Citation
N. Pfanner, Protein sorting: Recognizing mitochondrial presequences, CURR BIOL, 10(11), 2000, pp. R412-R415
Citations number
33
Categorie Soggetti
Experimental Biology
Journal title
CURRENT BIOLOGY
ISSN journal
09609822 → ACNP
Volume
10
Issue
11
Year of publication
2000
Pages
R412 - R415
Database
ISI
SICI code
0960-9822(20000601)10:11<R412:PSRMP>2.0.ZU;2-K
Abstract
The mitochondrial protein import machinery specifically recognizes many dif ferent preproteins lacking a consensus sequence. The three-dimensional stru cture of an import receptor complexed to an amino-terminal targeting 'prese quence' provides exciting insight into the molecular mechanism of signal re cognition.