Investigation of ultrasonic fibrin clot disruption in presence of streptoki
nase by methods of electron microscopy and nephelometry has revealed that a
t high sound power rate (6-10 W/cm(2)) and correspondingly short treatment
time (up to 1 min) mechanical clot degradation prevailed whereas enzymatic
lysis proceeded in parallel as the secondary process at much slower rate. U
pon termination of sonification procedure streptokinase acts mainly to prev
ent conglomeration of particles resulting from clot disintegration.