We examined clinical and epidemiological features of 575 laboratory-confirm
ed cases of vibrio gastroenteritis in Alabama, Florida, Louisiana, and Texa
s from 1988 to 1997 (the US Gulf of Mexico Regional Vibrio Surveillance Sys
tem). Illnesses occurred year round, with peaks in spring and autumn, Illne
sses lasted a median of 7 days and included fever in half of patients and b
loody stools in 25 % of patients with relevant information. Seventy-two per
cent of patients reported no underlying illnesses. In the week before onset
, 236 (53 %) of 445 patients for whom data were available ate raw oysters,
generally at a restaurant or bar. Educational efforts should address the ri
sk of vibrio gastroenteritis for raw oyster consumers, including healthy in
dividuals. Further studies should examine environmental conditions affectin
g vibrio counts on seafood and processing technologies to enhance the safet
y of raw oysters.