Background: Eighteen patients with unstable angina underwent repeat myocard
ial revascularization without cardiopulmonary bypass using saphenous vein g
rafts from either the left (13) or right (2) axillary arteries or the desce
nding thoracic aorta (3). Patients' ages ranged from 53 to 85 years. Left v
entricular ejection fractions ranged from 15% to 60%.
Methods: In 14 patients, the heart was exposed through an anterior thoracot
omy, a minimally invasive direct coronary artery bypass (MIDCAB) technique.
In 3 patients a left posterolateral thoractomy (lateral MIDCAB) was perfor
med. One patient underwent repeat sternotomy (off-pump coronary artery bypa
ss: OPCAB). In MIDCAB and lateral MIDCAB patients, the "target" vessel was
a coronary artery in 8 patients and a previously placed vein graft in the r
emaining 9 patients. One patient underwent repeat sternotomy, and 3 coronar
y arteries were bypassed with a complex vein graft attached to the left axi
llary artery. Two patients died of mesenteric ischemia on the 2nd and 7th p
ostoperative day. The remainder of patients were discharged from the hospit
al free of angina. Early graft patency was demonstrated by noninvasive vasc
ular laboratory testing and/or angiography in the 13 survivors in whom the
axillary artery had been the site of the proximal anastomosis.
Results: Follow-up ranged from 1 to 25 months. No other patients have died,
and none have undergone additional surgical or catheter-based procedures.
Three patients have developed recurrent angina, and in 4 patients the extra
anatomic bypass grafts have apparently become occluded.
Conclusion: Extra-anatomic, off-pump bypass from the axillary artery or des
cending thoracic aorta to one or more coronary arteries can be performed sa
fely in seriously ill patients requiring a repeat bypass procedure. The ear
ly results, regarding relief of angina, are encouraging.