PULSATILE AND NONPULSATILE EXTRACORPOREAL-CIRCULATION USING CAPIOX(R)E TERUMO OXYGENATOR - A COMPARISON STUDY WITH ULTROX(R) AND MAXIMA(R) MEMBRANE OXYGENATORS

An open randomised, prospective study was undertaken on 90 patients wh o underwent routine myocardial revascularization. The aim of the study was to demonstrate that the Capiox(R)E polypropylene fiber membrane o xygenator with a conventional single pulsatile/nonpulsatile blood pump for cardiopulmonary bypass (CPB) was comparable in performance to tha t of the Maxima(R) and the Ultrox(R) membrane oxygenators using a doub le pump system, The patients were divided into six groups according to perfusion mode and oxygenator type. Laboratory parameters, fluid bala nce and oxygenation was examined at set times before during and after cardiopulmonary bypass. Net fluid input was lower in the Capiox(R)E gr oups regardless of perfusion mode: 2932+/-562 ml (Capiox(R)E), compare d to 3646+/-531 ml (Ultrox(R)) and 3593+/-582 ml (Maxima(R)). Net flui d balance 1288+/-534 ml was lowest in the Capiox(R)/NP group, compared to 1604+/-460 ml (Ultrox(R)/NP) and 1881+/-594 ml (Maxima(R)/NP), (p< 0.05). The higher net fluid balance in the Capiox(R)E/PP group 1649+/- 580 ml compared to 1592+/-583 ml (Ultrox(R)E/PP) and 1494+/-542 ml (Ma xima(R)/PP) was attributed to a technicality whereby the recommended p riming volume of the Capiox(R)E oxygenator was exceeded for safety rea sons, The values of plasma free Hb were slightly higher in the PP than NP groups: Maxima(R)/PP 80 mg/dl, /NP 50 mg/dl; Ultrox(R)/PP 62 mg/dl , /NP 48 mg/dl; Capiox(R)E /PP 55 mg/dl /NP 48 mg/dl. The FiO(2) was h igher in the Capiox(R)E groups 0.77 (PP) and 0.88 CNP) compared to Max ima(R) /PP (0.66), /NP (0.65) and Ultrox(R) /PP (0.64), /NP (0.63). Re ciprocally, the venous saturation was higher in the Ultrox(R) and Maxi ma(R) groups compared to Capiox(R)E at end of CPB, The study demonstra ted that the Capiox(R)E oxygenator with a single blood pump system can compare to the Maxima(R) and Ultrox(R) oxygenators with a double bloo d pump for CPB with regard to blood handling, oxygenation and fluid ba lance in routine cardiac surgery.