Antifeedant activity of withanolides from Salpichroa origanifolia on Muscadomestica

Authors
Mareggiani, G Picollo, MI Zerba, E Burton, G Tettamanzi, MC Benedetti-Doctorovich, MOV Veleiro, AS
Citation
G. Mareggiani et al., Antifeedant activity of withanolides from Salpichroa origanifolia on Muscadomestica, J NAT PROD, 63(8), 2000, pp. 1113-1116
Citations number
14
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
8
Year of publication
2000
Pages
1113 - 1116
Database
ISI
SICI code
0163-3864(200008)63:8<1113:AAOWFS>2.0.ZU;2-7
Abstract
The antifeedant effect of several salpichrolides on larvae of Musca domesti ca was investigated. Three naturally occurring compounds, salpichrolide A. (1), salpichrolide C (2), and salpichrolide G (3), previously isolated from Salpichroa origanifolia, and two known (4, 6) and three new (5, 7, 8) synt hetic analogues were tested. The maximal effect on development was observed for salpichrolide A (1), while salpichrolide G (3) was the most toxic. The content of the salpichrolides in S. origanifolia was monitored by HPLC dur ing plant development, reaching a maximum during summer.