Background: Histologically proven radical resections are the goal in patien
ts with head and neck cancer because of improved survival rates. The freque
ncy of histologically radical resections using the median mandibulotomy and
the morbidity of this approach for tumors of the oropharynx and the paraph
aryngeal space are described in a patients series. Methods: The follow-up i
ncludes 16 consecutive patients who were operated on by a median mandibulot
omy approach between 1995 and 1998. The oncological benefit ( tumor free ma
rgins), complications and the functional results (ability of opening the mo
uth, mastication, swallowing, speech, cosmesis and pain) were reviewed. Res
ults: In 15/16 cases a histological radical resection was achieved. 14 pati
ents were irradiated postoperatively. In this group 3 patients had an osteo
radionecrosis, one an osteomyelitis of the mandible. The functional results
were worse in more advanced tumors. Conclusion: The indications for a medi
an mandibulotomy are primarily T3 and T4 tumors of the oral cavity and orop
harynx, rarely expansive benign parapharyngeal tumors. In most cases a hist
ological radical resection is achieved even in advanced tumors, probably du
e to the wide exposure of the involved area. in contrast this approach is a
ssociated with a high morbidity.