F. El Sayyad et al., Nonpenetrating deep sclerectomy versus trabeculectomy in bilateral primaryopen angle glaucoma, OPHTHALMOL, 107(9), 2000, pp. 1671-1674
Objective: To establish the efficacy and safety of nonpenetrating deep scle
rectomy versus trabeculectomy in primary open-angle glaucoma.
Design: Prospective randomized trial.
Participants: Thirty-nine patients (78 eyes) with bilateral primary open an
gle glaucoma were included in the study.
Intervention: Eyes were randomly assigned to receive deep sclerectomy in on
e eye and trabeculectomy in the other eye.
Main Outcome Measures: Mean intraocular pressure (IOP), postoperative medic
ations, visual acuity, success rate, and complications.
Results: At 12 months, mean IOP reduction was 12.3 +/- 4.2 (sclerectomy) ve
rsus 14.1 +/- 6.4 mmHg (trabeculectomy) (P = 0.15), and an IOP less than or
equal to 21 mmHg was achieved in 36 (92.3%) and 37 eyes (94.9%) (P = 0.9),
respectively. Complications included three (7.7%) flat/shallow anterior ch
ambers and one (2.6%) hypotony (trabeculectomy), whereas internal iris inca
rceration was encountered in two eyes (5.1%) (sclerectomy).
Conclusions: Deep sclerectomy may provide comparable IOP reduction with few
er complications in management of primary open angle glaucoma. Ophthalmolog
y 2000;107:1671-1674 (C) 2000 by the American Academy of Ophthalmology.