Angiomyomatous amartoma and associated stromal lesions in the right inguinal lymph node: A case report

Angiomyomatous hamartoma is a rare disease with a predisposition for the in guinal lymph nodes. A 51-year-old male patient visited a local hospital bec ause of a right inguinal mass, measuring 3 x 4 cm in size, which was resect ed. The resected specimen showed irregularly distributed thick-walled vesse ls in the hilum, extending into the medulla and focally into the cortex of the node, eventually becoming more dispersed and associated with smooth mus cle cells splaying into sclerotic stroma. These findings are compatible wit h an angiomyomatous hamartoma. Another tumor-like mass appeared shortly aft er the resection at the same location, but was not an angiomyomatous hamart oma, rather it was composed of edematous stromal tissue with proliferating smooth muscle cells. The stromal component included thick-walled blood vess els and lymphatics. Although it could not be determined whether these assoc iated changes in the surrounding stroma are a cause or an effect of angiomy omatous hamartoma, they indicate the clinical difficulty in determining an appropriate area of resection and may provide clues to the pathogenesis of angiomyomatous hamartoma.