DERIVATIVES OF NATURAL TETRAPYRROLES FOR PHOTODYNAMIC THERAPY .4. OXIDATIVE-DEGRADATION STUDIES - DIRECT ANALYSIS AND DETERMINATION OF ETHER AND ESTER LINKAGES IN PORPHYRIN DIMERS AND OLIGOMERS OF HEMATOPORPHYRIN DERIVATIVE (HPD)

Oxidative degradation studies of dimeric porphyrins provide valuable i nformation about the individual linkages between the porphyrin units. MS and NMR data of the degradation products of hematoporphyrin derivat ive furnish unambiguous evidence of ester and ether linkages in the di - and oligomeric compounds of HPD.