Neutral and basic taxoid contents in the needles of Taxus species

Authors
Poupat, C Hook, I Gueritte, F Ahond, A Guenard, D Adeline, MT Wang, XP Dempsey, D Breuillet, S Potier, P
Citation
C. Poupat et al., Neutral and basic taxoid contents in the needles of Taxus species, PLANTA MED, 66(6), 2000, pp. 580-584
Citations number
13
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PLANTA MEDICA
ISSN journal
00320943 → ACNP
Volume
66
Issue
6
Year of publication
2000
Pages
580 - 584
Database
ISI
SICI code
0032-0943(200008)66:6<580:NABTCI>2.0.ZU;2-Q
Abstract
The concentrations of paclitaxel, 10-deacetylbaccatin III (10-DAB III), bas ic taxoids (= "total alkaloids", TA), taxine B and isotaxine 8 (= "taxines B", TBS) in the dried needles of 127 trees belonging to 30 Taxus cultivars and species were determined by HPLC. Neutral and basic taxoid contents vari ed in individual trees within species as well as among varieties and specie s. The objective of this large analysis was to select the highest-yielding trees for each metabolite.