Pinnamine, an alkaloidal marine toxin, isolated from Pinna muricata

Authors
Takada, N Iwatsuki, M Suenaga, K Uemura, D
Citation
N. Takada et al., Pinnamine, an alkaloidal marine toxin, isolated from Pinna muricata, TETRAHEDR L, 41(33), 2000, pp. 6425-6428
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
33
Year of publication
2000
Pages
6425 - 6428
Database
ISI
SICI code
0040-4039(20000812)41:33<6425:PAAMTI>2.0.ZU;2-K
Abstract
Pinnamine, a novel marine alkaloid, was isolated from the Okinawan bivalve Pinna muricata. Pinnamine was determined to be an alkaloid containing a dih ydropyrone ring by spectroscopic analysis. The relative stereostructure of pinnamine was determined by an analysis of coupling constants and NOE exper iments; the absolute stereostructure was determined by an analysis of the c ircular dichroism spectrum. Pinnamine exhibited significant acute toxicity against mice. (C) 2000 Elsevier Science Ltd. All rights reserved.