Identification of a new HLA-B*78 allele in a Hispanic family

Authors
Gaidulis, L Krausa, P Schaub, B Senitzer, D
Citation
L. Gaidulis et al., Identification of a new HLA-B*78 allele in a Hispanic family, TISSUE ANTI, 56(2), 2000, pp. 184-187
Citations number
7
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
TISSUE ANTIGENS
ISSN journal
00012815 → ACNP
Volume
56
Issue
2
Year of publication
2000
Pages
184 - 187
Database
ISI
SICI code
0001-2815(200008)56:2<184:IOANHA>2.0.ZU;2-5
Abstract
A new B*78 variant, B*7804, was detected in three members of a Hispanic fam ily. The novel B*78 sequence differs from B*78021 by two substitutions: T a t nucleotide 527 (all other B*78s have A) and T at nucleotide 583 (all othe r B*78s have a C). Both nucleotide substitutions encode amino acid changes at codons 152 and 171, respectively.