Background: Despite knowledge about compromised host defence in the course
of diabetes mellitus and pancreatitis, epidural analgesia (EA) is recommend
ed for pain management during pancreatitis.
Case report: We present the case of a diabetic patient with pancreatitis wh
o developed an epidural abscess after 3 days with an epidural catheter. Nat
ural killer and T-helper cell counts were distinctively reduced in the abse
nce of HIV serology. Furthermore, a synthesis failure of the liver was obse
rved and evidenced by low cholinesterase, low whole protein fraction and lo
w antithrombin III in the peripheral blood.
Conclusion: We suggest that the combination of pancreatitis, diabetes and c
ompromised immunity might be a contraindication to epidural analgesia.