Fifty-one children (median age: 4.5 years; 4 months-16 years) diagnosed wit
h rhabdomyosarcoma were treated in our center between 1980-1999. The primar
y sites were head and neck in 31.4%, the genito-urinary system in 21.6%, an
d extremities in 9.8% of the patients. The histopathologic subtypes were em
bryonal in 80.4%, alveolar in 9.8%, and undifferentiated in 9.8%. The major
ity of the patients were considered group III (47%) and group IV (25.5%) ac
cording the criteria of the Intergroup Rhabdomyosarcoma Study (IRS). Primar
y total tumour resection was performed in only 27.5% of the patients. The p
atients were treated with assigned regimens of IRS II and IRS III protocols
. Radiotherapy was applied to 92.1% of the patients. Thirty-four patients (
66.7%) were lost to follow up, and of the remaining 17 patients, 7 patients
(41.2%) died, relapse occurred in 9 patients (52.9%) and 10 patients (58.8
%) are alive. The percentage of cases lost to follow up during the first 10
years and the following 9 years of the study were 77.4% and 50%, respectiv
ely. Incompliance with cancer treatment remains a major problem in developi
ng countries.