Background: Preoxygenation before tracheal intubation is intended to increa
se oxygen reserves and delay the onset of hypoxemia during apnea. Various s
ystems are used for preoxygenation, Designed specifically for preoxygenatio
n, the NasOral system uses a small nasal mask for inspiration and a mouthpi
ece for exhalation, One-way valves in the nasal mask and the mouthpiece ens
ure unidirectional flow. This investigation compares the efficacy of preoxy
genation using the standard circle system with the NasOral system and five
different resuscitation bags.
Methods: Twenty consenting, healthy volunteers were studied in the supine p
osition for 5-min periods of tidal volume breathing using the circle absorb
er system, the NasOral system, and five resuscitation bags in a randomized
order. Data were collected during room air breathing and at 30-s intervals
during 5 min of oxygen administration. Inspired oxygen, end-tidal oxygen, a
nd end-tidal nitrogen were measured by mass spectrometry.
Results: At 2.5 min of oxygenation, end-tidal oxygen plateaued at 88.1 +/-
4.8 and 89.3 +/- 6.4% (mean +/- SD) for the circle absorber and NasOral sys
tems, respectively. This was associated with inverse decreases in end-tidal
nitrogen. At no time did these end-tidal oxygen or nitrogen values differ
from each other. Three of the resuscitation bags (one disk type and two duc
k-bill type with one-way exhalation valves) delivered inspired oxygen more
than 90%, and the end-tidal oxygen plateaued between 77 and 89% at 2 min of
tidal volume breathing. The other two resuscitation bags (both duck-bill b
ags without exhalation valves) delivered inspired oxygen less than 40%, and
the end-tidal oxygen values ranged between 21.8 +/- 5.0 and 31.9 +/- 8.7%.
Conclusions: The circle absorber and NasOral systems were equally effective
in achieving maximal preoxygenation during tidal volume breathing. Resusci
tation bags differed markedly in effectiveness during preoxygenation; those
with duck-bill valves without one-way exhalation valves were the least eff
ective. Thus, the use of these bags should be avoided for preoxygenation.