Creating an interatrial shunt to achieve left-right flow balance and modifi
cation of the blood chambers to improve the basic performance of the device
were performed in developing an eccentric roller type total artificial hea
rt (ERTAH). Smaller blood chambers reduce friction loss and increase durabi
lity and energy efficiency. We changed the left blood chamber volume of 60
ml to 40 ml and the right blood chamber volume of 53 ml to 35 ml compared w
ith previous types. Designs of inlet and outlet ports were modified to prev
ent backflow. In the mock circulatory system, redesigning the blood chamber
s resulted in a 20% increase in energy efficiency, about a two-fold increas
e of cardiac output and improved durability compared to the previous type.
In an animal experiment, the ERTAH operated at a driving rate of 160 rpm wi
th a left flow rate of 6.0 L/min and a right flow rate of 5.4 L/min. Intera
trial shunt flow rate was 250-400 ml/min.