Recent observations of the Vela SNR in the ISM species Ca II and Na I are p
resented and discussed in the context of the "break-down'' of the Spitzer-R
outly effect. Variations in line profiles with time are demonstrated, event
ually through a statistical approach a description of cloud structure will
be possible. The IS lines in similar to 70 sightlines are used to determine
an accurate distance to the Vela SNR of 250 +/- 30 pc. Finally a discussio
n of future observations are given relating information obtained from measu
rements of near-by ISM to more distant intergalactic medium.