Vestibular function, along with other sensory systems influencing spatial o
rientation, can have a profound influence on the ability of astronauts to f
unction effectively. Beyond the well-known problems of space motion sicknes
s, vestibular effects can influence astronaut wellbeing and performance dur
ing ail phases of a space mission, This paper discusses some of the major v
estibular reactions affecting human factors encountered in all space missio
ns, and covers them chronologically in the following sequence: launch, earl
y on-orbit, late on-orbit EVA, artificial gravity, re-entry, and post-landi
ng.