Environmental enrichment from birth enhances visual acuity but not place learning in mice

The effect of richness of the environment on behavioral function was invest igated in C57B6 mice. Animals were raised in either enriched (group-housed in large clear plexiglas cages with stimulating objects) or restricted (gro up housed in opaque white plastic cages with no stimulating objects) enviro nmental conditions and their spatial learning and visual acuity were measur ed as adults. The performance of enriched and restricted groups were indist inguishable in place and cued versions of the Morris water task; however, t he visual acuity of the enriched group, measured in a grating versus gray v ersion of the visual water task, was 18% higher than the restricted group. These data demonstrate that the function of the mouse visual system can be significantly influenced by the nature of early visual input. They also ind icate that the effects of environmental enrichment are manifested different ly in behavioral measures of spatial learning and visual acuity. (C) 2000 E lsevier Science B.V. All rights reserved.