Identification of inorganic crystal-specific sequences using phage displaycombinatorial library of short peptides: A feasibility study

The feasibility of using a combinatorial phage display library of decapepti des to identify ligands which can interact with the surface of a crystal wa s assessed using geological calcium carbonate as a model. Two relatively st rong binding clones were identified by ELISA, sequenced and the encoded oli gopeptides were prepared by solid phase synthesis and their properties comp ared with those of casein hydrolysate.