F. Ballester et al., MORTALITY AS A FUNCTION OF TEMPERATURE - A STUDY IN VALENCIA, SPAIN, 1991-1993, International journal of epidemiology, 26(3), 1997, pp. 551-561
Background. Increased mortality is associated with both very low and v
ery high ambient temperatures. This study assesses the relationship be
tween daily numbers of deaths and variations in ambient temperature wi
thin the city of Valencia. Methods. The daily number of deaths from al
l causes (total deaths and only those occurring in people aged over 70
), as well as those deaths from specific causes (e.g. cardiovascular a
nd respiratory diseases, malignant tumours and all causes except exter
nal ones) occurring within the city of Valencia were related to the av
erage daily temperature using autoregressive Poisson regression contro
lling for seasonality, day of the week, holidays, air pollution, influ
enza incidence, and humidity. Temperature was measured within the regr
ession model as two complementary variables: 'Heat' and 'Cold'; also t
aken into account were their delayed effects up to 2 weeks after measu
rement. Results. Graphical analysis revealed a relationship between te
mperature and mortality according to the time of year. For the cooler
months (November-April), the temperature at which mortality was lowest
was the 'minimum' (i.e. around 15 degrees C), while for the warmer mo
nths (May-October), it occurred at around 24 degrees C. Because of thi
s, a stratified analysis was undertaken with different values for the
'Heat' and 'Cold' variables according to which of the two seasons was
involved. During the colder months of the year, higher temperatures te
nded to exert a rapid influence on mortality and the lower temperature
s a more delayed relation. During the hot season it is the heat variab
le which more clearly manifests an effect, and this is prolonged over
the two following weeks. Variations also occur according to age and ca
use of death. The effect of temperature is greater in persons aged ove
r 70 years of age, and it is also greater in cases of circulatory and
respiratory diseases. Conclusions. A statistically significant associa
tion has been found between temperature and mortality. This relationsh
ip is not monotonic, but mortality increases in proportion to the vari
ance in ambient temperature from a range of temperatures that varies f
rom winter to summer.